NFL Week 10 betting odds: Lines and totals for every game

Week 10 gets underway with the NFC East-leading New York Giants hosting the Washington Commanders on Thursday night at MetLife Stadium. These teams played to a 27-27 tie in Week 5 after a Commanders gaffe in overtime allowed time to expire. The Giants are slight favorites in the rematch.

The New England Patriots and Detroit Lions meet in Munich to get the Sunday slate started. The Jacksonville Jaguars are the biggest favorites of the week, laying 9.5 points Sunday afternoon on the road against the Tennessee Titans. The San Francisco 49ers-Dallas Cowboys matchup in the late afternoon window has the highest total (55.5).

The winless Los Angeles Chargers will visit the Baltimore Ravens on "Monday Night Football" (8:15 p.m. ET on ESPN) to close out the week.

The Chicago Bears, Denver Broncos, Philadelphia Eagles and Tampa Bay Buccaneers are on byes. Here's a look at the odds for every game this week.

Jump to:

WSH-NYG | NE-DET | BUF-NYJ | KC-ATL

MIA-IND | JAX-TEN | MIN-GB | CAR-NO

HOU-CLE | LAR-ARI | SEA-LV | SF-DAL

PIT-CIN | LAC-BAL

Moneyline: Commanders (+105); Giants (-125)

Total: 43.5; Opened: 47.5

FPI favorite: Commanders by 0.2 with a 51% probability to win the game outright

Moneyline: Patriots (+120); Lions (-142)

Total: 50.5; Opened: 48.5

FPI favorite: Patriots by 0.4 with a 51% probability to win the game outright

Moneyline: Bills (-550); Jets (+410)

Total: 51.5; Opened: 46.5

FPI favorite: Bills by 7.6 with a 77% probability to win the game outright

Check out the latest Super Bowl odds and major NFL awards futures.

Moneyline: Chiefs (-180); Falcons (+150)

Total: 46.5; Opened: 45.5

FPI favorite: Chiefs by 6.1 with a 73% probability to win the game outright

Moneyline: Dolphins (+110); Colts (-130)

Total: 41.5; Opened: 47.5

FPI favorite: Colts by 5.5 with a 71% probability to win the game outright

Moneyline: Jaguars (-500); Titans (+380)

Total: 46.5; Opened: 45.5

FPI favorite: Jaguars by 10 with an 84% probability to win the game outright

Moneyline: Vikings (+142); Packers (-170)

Total: 42.5; Opened: 45.5

FPI favorite: Packers by 1.7 with a 57% probability to win the game outright

Moneyline: Panthers (-120); Saints (+100)

Total: 47.5; Opened: 43.5

FPI favorite: Saints by 0.2 with a 51% probability to win the game outright

Moneyline: Texans (-192); Browns (+160)

Total: 39.5; Opened: 38.5

FPI favorite: Texans by 5.5 with a 70% probability to win the game outright

Moneyline: Rams (-310); Cardinals (+250)

Total: 45.5; Opened: 47.5

FPI favorite: Rams by 8.1 with a 79% probability to win the game outright

Moneyline: Seahawks (-166); Raiders (+140)

Total: 42.5; Opened: 43.5

FPI favorite: Seahawks by 3.6 with a 64% probability to win the game outright

Moneyline: 49ers (-225); Cowboys (+185)

Total: 55.5; Opened: 52.5

FPI favorite: 49ers by 3.3 with a 63% probability to win the game outright

Moneyline: Steelers (+142); Bengals (-170)

Total: 47.5; Opened: 47.5

FPI favorite: Bengals by 4.7 with a 68% probability to win the game outright

Moneyline: Chargers (+154); Ravens (-185)

Total: 38.5; Opened: 48.5

FPI favorite: Chargers by 1.8 with a 57% probability to win the game outright