Sources: 49ers Pro Bowl FB Juszczyk (knee) expected out 2-3 weeks

ByNick WagonerESPN logo
Monday, October 5, 2026 7:25PM

SANTA CLARA, Calif. -- San Francisco 49ers Pro Bowl fullback Kyle Juszczyk suffered a knee sprain and bone bruise that is expected to sideline him for two to three weeks, sources told ESPN's Adam Schefter and NFL Network's Ian Rapoport.

Juszczyk sustained the injury during San Francisco's 24-14 victory over the Denver Broncos on Sunday. An MRI performed Monday confirmed the nature of his injury.

With 14:03 to go, Niners quarterback Brock Purdy scrambled to his left and found Juszczyk open down the sideline for a 16-yard gain. Broncos defensive back Jahdae Barron delivered a big hit to Juszczyk's knee and midsection, and Juszczyk stayed down for a few minutes as the Niners medical team rushed to help.

Niners personnel helped Juszczyk to the sideline, where he entered the medical tent and stayed for a bit before watching the rest of the game on the bench. The 49ers quickly ruled out a potential return for Juszczyk, who finished with two catches for 28 yards.

Juszczyk, who has been selected to the past 10 Pro Bowls, has four receptions for 55 yards and a touchdown this season.

Safety Marques Sigle (ankle) and slot cornerback Upton Stout (shoulder) also suffered injures Sunday that did not allow them to finish the game.

Sigle suffered a pair of injuries Sunday, initially departing early in the third quarter with a stinger. He returned on Denver's next possession but was injured with 2:15 left when he hurt his ankle near Denver's sideline. He did not return after making six tackles on the day.

Stout hurt his shoulder in the third quarter and jogged to the locker room to be evaluated soon after Juszczyk's injury early in the fourth. Stout returned with 2:07 to go but then left again and did not play during the Broncos' final few snaps. He also finished with six tackles.br/]

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